Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

You are viewing the site in preview mode

Skip to main content

Table 2 Multivariate Cox analysis of endpoint events in patients with diabetic kidney disease

From: Association between magnesium depletion score and all-cause and cause-specific mortality in patients with diabetic kidney disease

 

Events/Total

Model 1

Model 2

Model 3

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

All-cause mortality

2052/3179

      

 MDS = 0

35/89

Reference

0.003

Reference

0.002

Reference

0.004

 MDS = 1

116/212

1.581(1.083,2.307)

0.018

1.531(1.049,2.235)

0.027

1.724(1.178,2.523)

0.005

 MDS = 2

1675/2509

1.809(1.294,2.529)

< 0.001

1.825(1.305,2.551)

< 0.001

1.864(1.321,2.631)

< 0.001

 MDS ≥ 3

226/369

1.730(1.212,2.407)

0.003

1.767(1.237,2.523)

0.002

1.932(1.339,2.787)

< 0.001

Cardiovascular mortality

690/3179

      

 MDS = 0

6/89

Reference

0.008

Reference

0.006

Reference

0.015

 MDS = 1

37/212

2.908(1.227,6.892)

0.015

2.798(1.180,6.631)

0.019

3.391(1.428,8.054)

0.006

 MDS = 2

575/2509

3.613(1.616,8.078)

0.002

3.648(1.631,8.156)

0.002

3.839(1.700,8.672)

0.002

 MDS ≥ 3

72/369

3.191(1.387,7.341)

0.006

3.669(1.421,7.521)

0.005

3.688(1.586,8.577)

< 0.001

  1. Note: HR, hazard ratio; CI, confidence interval;
  2. Model 1: unadjusted model
  3. Model 2: adjusted for age and sex
  4. Model 3: adjusted for age, sex, race, Blood glucose control, BMI, Magnesium intake, Heavy drinking, HbA1c, TC, TG, HDL-C, FBG, Serum phosphorus, Statins use, Insulin use, Metformin use, Diuretic use, PPI use, eGFR, Hypertension and CVD